ea0056gp193 | Pituitary / Growth Hormone ' IGF Axis | ECE2018
van den Berg Gerrit
, van den Brom Rob
, van der Klauw Melanie
, Hiltermann Jeroen
, Hospers Geke
, Links Thera
Hypophysitis is one of the immune-related adverse events of immune checkpoint blockade. This complication is potentially dangerous, mainly because of the insidious development of a life-threatening hypocortisolism. Unnecessary morbidity or mortality in an oncological responder may be the result. The number of patients treated with immune checkpoint inhibitors increases rapidly, due to the expansion of indications and trials. Moreover, the introduction of combination schedules ...